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AICAR inhibits adipocyte differentiation in 3T3L1 and restores metabolic alterations in diet-induced obesity mice model
BACKGROUND: Obesity is one of the principal causative factors involved in the development of metabolic syndrome. AMP-activated protein kinase (AMPK) is an energy sensor that regulates cellular metabolism. The role of AMP-activated protein kinase in adipocyte differentiation is not completely underst...
Autores principales: | Giri, Shailendra, Rattan, Ramandeep, Haq, Ehtishamul, Khan, Mushfiquddin, Yasmin, Rifat, Won, Je-song, Key, Lyndon, Singh, Avtar K, Singh, Inderjit |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564022/ https://www.ncbi.nlm.nih.gov/pubmed/16901342 http://dx.doi.org/10.1186/1743-7075-3-31 |
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