Parameter estimation for stiff equations of biosystems using radial basis function networks

BACKGROUND: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for parameter estimation, e.g. genetic algorithms (GA), consume enormous computational time because they require iterative numer...

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Detalles Bibliográficos
Autores principales: Matsubara, Yoshiya, Kikuchi, Shinichi, Sugimoto, Masahiro, Tomita, Masaru
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1564045/
https://www.ncbi.nlm.nih.gov/pubmed/16643665
http://dx.doi.org/10.1186/1471-2105-7-230

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