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The role of DNA sequence in centromere formation
Centromeres are key to the correct segregation and inheritance of genetic information. Eukaryotic centromeres, which are located in large blocks of highly repetitive DNA, have been notoriously difficult to sequence. Several groups have recently succeeded in analyzing centromeric sequences in human,...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC156579/ https://www.ncbi.nlm.nih.gov/pubmed/12734002 http://dx.doi.org/10.1186/gb-2003-4-5-214 |
| _version_ | 1782120776450703360 |
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| author | Lamb, Jonathan C Birchler, James A |
| author_facet | Lamb, Jonathan C Birchler, James A |
| author_sort | Lamb, Jonathan C |
| collection | PubMed |
| description | Centromeres are key to the correct segregation and inheritance of genetic information. Eukaryotic centromeres, which are located in large blocks of highly repetitive DNA, have been notoriously difficult to sequence. Several groups have recently succeeded in analyzing centromeric sequences in human, Drosophila and Arabidopsis, providing new insights into the importance of DNA sequence for centromere function. |
| format | Text |
| id | pubmed-156579 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2003 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-1565792003-06-05 The role of DNA sequence in centromere formation Lamb, Jonathan C Birchler, James A Genome Biol Minireview Centromeres are key to the correct segregation and inheritance of genetic information. Eukaryotic centromeres, which are located in large blocks of highly repetitive DNA, have been notoriously difficult to sequence. Several groups have recently succeeded in analyzing centromeric sequences in human, Drosophila and Arabidopsis, providing new insights into the importance of DNA sequence for centromere function. BioMed Central 2003 2003-04-29 /pmc/articles/PMC156579/ /pubmed/12734002 http://dx.doi.org/10.1186/gb-2003-4-5-214 Text en Copyright © 2003 BioMed Central Ltd |
| spellingShingle | Minireview Lamb, Jonathan C Birchler, James A The role of DNA sequence in centromere formation |
| title | The role of DNA sequence in centromere formation |
| title_full | The role of DNA sequence in centromere formation |
| title_fullStr | The role of DNA sequence in centromere formation |
| title_full_unstemmed | The role of DNA sequence in centromere formation |
| title_short | The role of DNA sequence in centromere formation |
| title_sort | role of dna sequence in centromere formation |
| topic | Minireview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC156579/ https://www.ncbi.nlm.nih.gov/pubmed/12734002 http://dx.doi.org/10.1186/gb-2003-4-5-214 |
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