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Characterization of rabbit myocilin: Implications for human myocilin glycosylation and signal peptide usage

BACKGROUND: Mutations in the gene encoding human myocilin (MYOC) have been shown to cause juvenile- and adult-onset glaucoma. In addition, myocilin has been associated with glucocorticoid-induced ocular hypertension and steroid-induced glaucoma. To better understand the role myocilin plays in steroi...

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Detalles Bibliográficos
Autores principales: Shepard, Allan R, Jacobson, Nasreen, Sui, Ruifang, Steely, H Thomas, Lotery, Andrew J, Stone, Edwin M, Clark, Abbot F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC156599/
https://www.ncbi.nlm.nih.gov/pubmed/12697062
http://dx.doi.org/10.1186/1471-2156-4-5

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