Cargando…
Characterization of rabbit myocilin: Implications for human myocilin glycosylation and signal peptide usage
BACKGROUND: Mutations in the gene encoding human myocilin (MYOC) have been shown to cause juvenile- and adult-onset glaucoma. In addition, myocilin has been associated with glucocorticoid-induced ocular hypertension and steroid-induced glaucoma. To better understand the role myocilin plays in steroi...
Autores principales: | Shepard, Allan R, Jacobson, Nasreen, Sui, Ruifang, Steely, H Thomas, Lotery, Andrew J, Stone, Edwin M, Clark, Abbot F |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2003
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC156599/ https://www.ncbi.nlm.nih.gov/pubmed/12697062 http://dx.doi.org/10.1186/1471-2156-4-5 |
Ejemplares similares
-
Cellular Processing of Myocilin
por: Qiu, Ye, et al.
Publicado: (2014) -
Heterozygous expression of myocilin glaucoma mutants increases secretion of the mutant forms and reduces extracellular processed myocilin
por: Aroca-Aguilar, José-Daniel, et al.
Publicado: (2008) -
Myocilin mutations in black South Africans with POAG
por: Whigham, Benjamin T., et al.
Publicado: (2011) -
A Role for Myocilin in Receptor-Mediated Endocytosis
por: McKay, Brian S., et al.
Publicado: (2013) -
Another Piece of the Puzzle: MYOC and Myocilin Glaucoma
por: Fini, M. Elizabeth
Publicado: (2017)