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Potential role of environmental factors in the etiology and pathogenesis of atopy: a working model.
Sensitization to inhalant allergens commonly commences in utero, and most children are born with weak T helper-2 (Th2)-polarized T-cell immunity to these agents. During early life, these responses are normally deviated toward the Th1 cytokine profile. However, in atopics this immune deviation proces...
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| Formato: | Texto |
| Lenguaje: | English |
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1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566234/ https://www.ncbi.nlm.nih.gov/pubmed/10346996 |