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Structure determination of human Lck unique and SH3 domains by nuclear magnetic resonance spectroscopy
BACKGROUND: Protein tyrosine kinases are involved in signal transduction pathways that regulate cell growth, differentiation, activation and transformation. Human lymphocyte specific kinase (Lck) is a 56 kDa protein involved in T-cell- and IL2-receptor signaling. Three-dimensional structures are kno...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC156628/ https://www.ncbi.nlm.nih.gov/pubmed/12734017 http://dx.doi.org/10.1186/1472-6807-3-3 |