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Role of renal metabolism in risk to toxic chemicals.
The kidneys are capable of carrying out extensive oxidation, reduction, hydrolysis, and conjugation reactions. Renal cortex has high activities of cytochrome P450 and glutathione (GSH) S-transferase. In contrast, renal medulla has high activity of prostaglandin synthetase, which can catalyze co-oxid...
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
1994
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566771/ https://www.ncbi.nlm.nih.gov/pubmed/7737046 |