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Vitamin A modulation of xenobiotic-induced hepatotoxicity in rodents.
Vitamin A (VA, retinol) has been shown to modulate cells of the immune system. When rats are pretreated with VA (75 mg/kg/day) for 7 days, there is greatly potentiated liver damage upon subsequent exposure to hepatotoxicants such as CCl4. This potentiated damage can be blocked by superoxide dismutas...
Autores principales: | Hooser, S B, Rosengren, R J, Hill, D A, Mobley, S A, Sipes, I G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1994
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566794/ https://www.ncbi.nlm.nih.gov/pubmed/7698082 |
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