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Arylamines suppress their own activation and that of nitroarenes in V79 Chinese hamster cells by competing for acetyltransferases.

The effect of 2-aminofluorene (2-AF) on the toxicity of 2-aminoanthracene (2-AA) and 1,6-dinitropyrene (1,6-DNP) was studied in N-acetyltransferase-proficient V79-NHr1A2 cells genetically engineered for the expression of cytochrome P4501A2, and in wild-type V79-NH cells. 2-AA inhibited the growth of...

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Detalles Bibliográficos
Autores principales:	Kiefer, F, Cumpelik, O, Reen, R, Doehmer, J, Wiebel, F J
Formato:	Texto
Lenguaje:	English
Publicado:	1994
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566860/ https://www.ncbi.nlm.nih.gov/pubmed/7889866

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