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Reactions of oxidatively activated arylamines with thiols: reaction mechanisms and biologic implications. An overview.
Aromatic amines belong to a group of compounds that exert their toxic effects usually after oxidative biotransformation, primarily in the liver. In addition, aromatic amines also undergo extrahepatic activation to yield free arylaminyl radicals. The reactive intermediates are potential promutagens a...
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
1994
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566864/ https://www.ncbi.nlm.nih.gov/pubmed/7889834 |