Multiple comparisons in long-term toxicity studies.

Several multiple comparison procedures (MCPs) are discussed in relation to the specific formulation of type I and type II errors in toxicity studies and the typical one-way design control versus k treatment/dose groups. Examples for these MCPs are: the standard many-to-one MCP (Dunnett's proced...

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Detalles Bibliográficos
Autor principal: Hothorn, L
Formato: Texto
Lenguaje:English
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566902/
https://www.ncbi.nlm.nih.gov/pubmed/8187721
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author Hothorn, L
author_facet Hothorn, L
author_sort Hothorn, L
collection PubMed
description Several multiple comparison procedures (MCPs) are discussed in relation to the specific formulation of type I and type II errors in toxicity studies and the typical one-way design control versus k treatment/dose groups. Examples for these MCPs are: the standard many-to-one MCP (Dunnett's procedure), sequential rejection modifications, closed testing procedures, many-to-one MCPs with an ordered alternative hypothesis, procedures based on the assumption of a mixing distribution of responders and nonresponders, and MCP's for multiple end points.
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spelling pubmed-15669022006-09-19 Multiple comparisons in long-term toxicity studies. Hothorn, L Environ Health Perspect Research Article Several multiple comparison procedures (MCPs) are discussed in relation to the specific formulation of type I and type II errors in toxicity studies and the typical one-way design control versus k treatment/dose groups. Examples for these MCPs are: the standard many-to-one MCP (Dunnett's procedure), sequential rejection modifications, closed testing procedures, many-to-one MCPs with an ordered alternative hypothesis, procedures based on the assumption of a mixing distribution of responders and nonresponders, and MCP's for multiple end points. 1994-01 /pmc/articles/PMC1566902/ /pubmed/8187721 Text en
spellingShingle Research Article
Hothorn, L
Multiple comparisons in long-term toxicity studies.
title Multiple comparisons in long-term toxicity studies.
title_full Multiple comparisons in long-term toxicity studies.
title_fullStr Multiple comparisons in long-term toxicity studies.
title_full_unstemmed Multiple comparisons in long-term toxicity studies.
title_short Multiple comparisons in long-term toxicity studies.
title_sort multiple comparisons in long-term toxicity studies.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566902/
https://www.ncbi.nlm.nih.gov/pubmed/8187721
work_keys_str_mv AT hothornl multiplecomparisonsinlongtermtoxicitystudies

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