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Induction of mutation spectra by complex mixtures: approaches, problems, and possibilities.
More complex environmental mixtures have been evaluated for mutagenic activity at the hisD3052 allele of Salmonella, primarily in strain TA98, than in any other target or mutation assay. Using colony probe hybridization to detect a common hot spot deletion, followed by polymerase chain reaction and...
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| Formato: | Texto |
| Lenguaje: | English |
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1994
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566946/ https://www.ncbi.nlm.nih.gov/pubmed/7821286 |