DNA adduct formation in relation to lymphocyte mutations and lung tumor induction in F344 rats treated with the environmental pollutant 1,6-dinitropyrene.

Epidemiological studies suggest an association between exposure to diesel emissions and an increased incidence of lung and bladder cancer in humans. Of the compounds associated with diesel emissions, 1,6-dinitropyrene is a particularly potent mutagen and carcinogen. In these experiments we administe...

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Detalles Bibliográficos
Autores principales: Smith, B A, Fullerton, N F, Aidoo, A, Heflich, R H, Beland, F A
Formato: Texto
Lenguaje:English
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567019/
https://www.ncbi.nlm.nih.gov/pubmed/8319643

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