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Identification of endogenous electrophiles by means of mass spectrometric determination of protein and DNA adducts.

Monitoring exposure to alkylating agents may be achieved by quantitatively determining the adduct levels formed with nucleic acids and/or proteins. One of the most significant results arising from the application of this approach has been the discovery in control populations of "background"...

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Detalles Bibliográficos
Autores principales: Farmer, P B, Bailey, E, Naylor, S, Anderson, D, Brooks, A, Cushnir, J, Lamb, J H, Sepai, O, Tang, Y S
Formato: Texto
Lenguaje:English
Publicado: 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567039/
https://www.ncbi.nlm.nih.gov/pubmed/8319621