Accumulation of O6-methylguanine in human DNA after therapeutic exposure to methylating agents and its relationship with biological effects.

O6-Methylguanine has been measured in peripheral blood leukocytes of 14 patients during one or more cycles of treatment with procarbazine (daily treatment for 10 days) and in 12 patients during one or more cycles of treatment with dacarbazine (single dose per cycle). Adduct formation at levels up to...

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Detalles Bibliográficos
Autores principales: Kyrtopoulos, S A, Souliotis, V L, Valavanis, C, Boussiotis, V A, Pangalis, G A
Formato: Texto
Lenguaje:English
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567067/
https://www.ncbi.nlm.nih.gov/pubmed/8319612

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