The cytochromes P450 and mechanisms of chemical carcinogenesis.

This article reviews mechanisms of chemical carcinogenesis, from metabolic activation and generation of reactive oxygen species by cytochromes P4511 and P4502E to DNA damage, activation of protein kinase C and ocogenes, hyperplasia, and proteoglycan changes in the cell glycocalyx and lysosomal enzym...

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Detalles Bibliográficos
Autor principal: Parke, D V
Formato: Texto
Lenguaje:English
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567360/
https://www.ncbi.nlm.nih.gov/pubmed/9644192
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author Parke, D V
author_facet Parke, D V
author_sort Parke, D V
collection PubMed
description This article reviews mechanisms of chemical carcinogenesis, from metabolic activation and generation of reactive oxygen species by cytochromes P4511 and P4502E to DNA damage, activation of protein kinase C and ocogenes, hyperplasia, and proteoglycan changes in the cell glycocalyx and lysosomal enzymes which mediate invasion and metastasis.
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spelling pubmed-15673602006-09-19 The cytochromes P450 and mechanisms of chemical carcinogenesis. Parke, D V Environ Health Perspect Research Article This article reviews mechanisms of chemical carcinogenesis, from metabolic activation and generation of reactive oxygen species by cytochromes P4511 and P4502E to DNA damage, activation of protein kinase C and ocogenes, hyperplasia, and proteoglycan changes in the cell glycocalyx and lysosomal enzymes which mediate invasion and metastasis. 1994-10 /pmc/articles/PMC1567360/ /pubmed/9644192 Text en
spellingShingle Research Article
Parke, D V
The cytochromes P450 and mechanisms of chemical carcinogenesis.
title The cytochromes P450 and mechanisms of chemical carcinogenesis.
title_full The cytochromes P450 and mechanisms of chemical carcinogenesis.
title_fullStr The cytochromes P450 and mechanisms of chemical carcinogenesis.
title_full_unstemmed The cytochromes P450 and mechanisms of chemical carcinogenesis.
title_short The cytochromes P450 and mechanisms of chemical carcinogenesis.
title_sort cytochromes p450 and mechanisms of chemical carcinogenesis.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567360/
https://www.ncbi.nlm.nih.gov/pubmed/9644192
work_keys_str_mv AT parkedv thecytochromesp450andmechanismsofchemicalcarcinogenesis
AT parkedv cytochromesp450andmechanismsofchemicalcarcinogenesis

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