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Transmembrane signals and protooncogene induction evoked by carcinogenic metals and prevented by zinc.
Cd2+ provokes an immediate production of inositol trisphosphate and the release of Ca2+ from internal stores in human fibroblasts and some other mammalian cells. Ni2+, Co2+, Fe2+, and Mn2+ evoke the release of stored Ca2+, but are less potent than Cd2+ (apparent K0.5 = 40 nM). Zn2+ and Cu2+ competit...
| Главные авторы: | , , , , |
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| Формат: | Текст |
| Язык: | English |
| Опубликовано: |
1994
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| Предметы: | |
| Online-ссылка: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567372/ https://www.ncbi.nlm.nih.gov/pubmed/7843095 |