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Development of an 125I-postlabeling assay as a simple, rapid, and sensitive index of DNA-protein cross-links.

A rapid, simple, and sensitive 125I-postlabeling technique has been developed to allow detection of DNA-protein cross-links induced by environmental contaminants and carcinogens. This method is based on specific incorporation of 125I into tyrosine residues associated with DNA. Cultured Chinese hamst...

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Detalles Bibliográficos
Autores principales: Zhuang, Z, Costa, M
Formato: Texto
Lenguaje:English
Publicado: 1994
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567398/
https://www.ncbi.nlm.nih.gov/pubmed/7843121