Multistage models for carcinogenesis.

The multistage model is tested on several human and animal data sets. It fits in some cases but not in others. With human lung cancer data, there is a drop in risk for ex-smokers quite different from the predictions of the model. The results are not conclusive but are compatible with the view that t...

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Detalles Bibliográficos
Autores principales: Freedman, D A, Navidi, W C
Formato: Texto
Lenguaje:English
Publicado: 1989
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567550/
https://www.ncbi.nlm.nih.gov/pubmed/2667978
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author Freedman, D A
Navidi, W C
author_facet Freedman, D A
Navidi, W C
author_sort Freedman, D A
collection PubMed
description The multistage model is tested on several human and animal data sets. It fits in some cases but not in others. With human lung cancer data, there is a drop in risk for ex-smokers quite different from the predictions of the model. The results are not conclusive but are compatible with the view that the multistage model provides a family of curves that often fit cancer incidence data, but may not capture the underlying biological reality.
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spelling pubmed-15675502006-09-18 Multistage models for carcinogenesis. Freedman, D A Navidi, W C Environ Health Perspect Research Article The multistage model is tested on several human and animal data sets. It fits in some cases but not in others. With human lung cancer data, there is a drop in risk for ex-smokers quite different from the predictions of the model. The results are not conclusive but are compatible with the view that the multistage model provides a family of curves that often fit cancer incidence data, but may not capture the underlying biological reality. 1989-05 /pmc/articles/PMC1567550/ /pubmed/2667978 Text en
spellingShingle Research Article
Freedman, D A
Navidi, W C
Multistage models for carcinogenesis.
title Multistage models for carcinogenesis.
title_full Multistage models for carcinogenesis.
title_fullStr Multistage models for carcinogenesis.
title_full_unstemmed Multistage models for carcinogenesis.
title_short Multistage models for carcinogenesis.
title_sort multistage models for carcinogenesis.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567550/
https://www.ncbi.nlm.nih.gov/pubmed/2667978
work_keys_str_mv AT freedmanda multistagemodelsforcarcinogenesis
AT navidiwc multistagemodelsforcarcinogenesis

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