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The development of applied action levels for soil contact: a scenario for the exposure of humans to soil in a residential setting.

The California Site Mitigation Decision Tree Manual, 1985, was developed by the California Department of Health Services to provide a detailed technical basis for managing uncontrolled hazardous waste sites. The Decision Tree describes a process that relies on criteria, Applied Action Levels (AALs)...

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Detalles Bibliográficos
Autor principal: Sedman, R M
Formato: Texto
Lenguaje:English
Publicado: 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567571/
https://www.ncbi.nlm.nih.gov/pubmed/2651104
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author Sedman, R M
author_facet Sedman, R M
author_sort Sedman, R M
collection PubMed
description The California Site Mitigation Decision Tree Manual, 1985, was developed by the California Department of Health Services to provide a detailed technical basis for managing uncontrolled hazardous waste sites. The Decision Tree describes a process that relies on criteria, Applied Action Levels (AALs) to evaluate and, if necessary, mitigate the impact of uncontrolled hazardous waste sites on the public health and the environment. AALs are developed for individual substances, species, and media of exposure. AALs have been routinely developed for the media of air and water; however, an approach for developing AALs for soil contact was lacking. Given that the air pathway for soil contact is addressed in AALs for air, two routes of exposure, ingestion and dermal contact, are addressed in developing AALs for soil contact. The approach assumes a lifetime of exposure to soil in a residential setting. Age-related changes in exposure are included in the scenario. Exposure to soil due to ingestion and dermal contact are quantitated independently and then integrated in the final exposure scenario. A mass balance approach using four elements is employed to quantitate soil ingestion for a young child. Changes in soil ingestion with age are based on age-related changes in blood lead concentration and mouthing behavior. Dermal exposure to soil was determined from studies that reported skin soil load and from estimates of exposed skin surface area. Age-related changes in the dermal exposure to soil are also based on changes with age of blood lead concentration and mouthing behavior. The estimates of exposure to soil due to ingestion and dermal contact are integrated, and an approach for developing AALs is advanced. AALs are derived by allocating the Maximum Exposure Level as described in the Decision Tree to the average daily exposure to soil. Toxicokinetic considerations for the two routes of exposure must be included in deriving AALs for the soil medium of exposure.
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spelling pubmed-15675712006-09-18 The development of applied action levels for soil contact: a scenario for the exposure of humans to soil in a residential setting. Sedman, R M Environ Health Perspect Research Article The California Site Mitigation Decision Tree Manual, 1985, was developed by the California Department of Health Services to provide a detailed technical basis for managing uncontrolled hazardous waste sites. The Decision Tree describes a process that relies on criteria, Applied Action Levels (AALs) to evaluate and, if necessary, mitigate the impact of uncontrolled hazardous waste sites on the public health and the environment. AALs are developed for individual substances, species, and media of exposure. AALs have been routinely developed for the media of air and water; however, an approach for developing AALs for soil contact was lacking. Given that the air pathway for soil contact is addressed in AALs for air, two routes of exposure, ingestion and dermal contact, are addressed in developing AALs for soil contact. The approach assumes a lifetime of exposure to soil in a residential setting. Age-related changes in exposure are included in the scenario. Exposure to soil due to ingestion and dermal contact are quantitated independently and then integrated in the final exposure scenario. A mass balance approach using four elements is employed to quantitate soil ingestion for a young child. Changes in soil ingestion with age are based on age-related changes in blood lead concentration and mouthing behavior. Dermal exposure to soil was determined from studies that reported skin soil load and from estimates of exposed skin surface area. Age-related changes in the dermal exposure to soil are also based on changes with age of blood lead concentration and mouthing behavior. The estimates of exposure to soil due to ingestion and dermal contact are integrated, and an approach for developing AALs is advanced. AALs are derived by allocating the Maximum Exposure Level as described in the Decision Tree to the average daily exposure to soil. Toxicokinetic considerations for the two routes of exposure must be included in deriving AALs for the soil medium of exposure. 1989-02 /pmc/articles/PMC1567571/ /pubmed/2651104 Text en
spellingShingle Research Article
Sedman, R M
The development of applied action levels for soil contact: a scenario for the exposure of humans to soil in a residential setting.
title The development of applied action levels for soil contact: a scenario for the exposure of humans to soil in a residential setting.
title_full The development of applied action levels for soil contact: a scenario for the exposure of humans to soil in a residential setting.
title_fullStr The development of applied action levels for soil contact: a scenario for the exposure of humans to soil in a residential setting.
title_full_unstemmed The development of applied action levels for soil contact: a scenario for the exposure of humans to soil in a residential setting.
title_short The development of applied action levels for soil contact: a scenario for the exposure of humans to soil in a residential setting.
title_sort development of applied action levels for soil contact: a scenario for the exposure of humans to soil in a residential setting.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567571/
https://www.ncbi.nlm.nih.gov/pubmed/2651104
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