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Coupling growth arrest and adipocyte differentiation.
The complete differentiation program of preadipose cells can be divided into early and late events. The expression of early markers takes place at growth arrest (G1/S boundary), whereas that of late markers, leading to terminal differentiation, takes place after a limited number of mitoses of early...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1989
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567619/ https://www.ncbi.nlm.nih.gov/pubmed/2647477 |
_version_ | 1782129865568288768 |
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author | Ailhaud, G Dani, C Amri, E Z Djian, P Vannier, C Doglio, A Forest, C Gaillard, D Négrel, R Grimaldi, P |
author_facet | Ailhaud, G Dani, C Amri, E Z Djian, P Vannier, C Doglio, A Forest, C Gaillard, D Négrel, R Grimaldi, P |
author_sort | Ailhaud, G |
collection | PubMed |
description | The complete differentiation program of preadipose cells can be divided into early and late events. The expression of early markers takes place at growth arrest (G1/S boundary), whereas that of late markers, leading to terminal differentiation, takes place after a limited number of mitoses of early marker-containing cells. Only terminal differentiation requires the presence of growth hormone and triiodothyronine and results in the formation of triacylglycerol-filled, nondividing cells. The events of adipose cell differentiation which take place in vitro allow a better understanding of the development of adipose tissue in vivo. |
format | Text |
id | pubmed-1567619 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1989 |
record_format | MEDLINE/PubMed |
spelling | pubmed-15676192006-09-18 Coupling growth arrest and adipocyte differentiation. Ailhaud, G Dani, C Amri, E Z Djian, P Vannier, C Doglio, A Forest, C Gaillard, D Négrel, R Grimaldi, P Environ Health Perspect Research Article The complete differentiation program of preadipose cells can be divided into early and late events. The expression of early markers takes place at growth arrest (G1/S boundary), whereas that of late markers, leading to terminal differentiation, takes place after a limited number of mitoses of early marker-containing cells. Only terminal differentiation requires the presence of growth hormone and triiodothyronine and results in the formation of triacylglycerol-filled, nondividing cells. The events of adipose cell differentiation which take place in vitro allow a better understanding of the development of adipose tissue in vivo. 1989-03 /pmc/articles/PMC1567619/ /pubmed/2647477 Text en |
spellingShingle | Research Article Ailhaud, G Dani, C Amri, E Z Djian, P Vannier, C Doglio, A Forest, C Gaillard, D Négrel, R Grimaldi, P Coupling growth arrest and adipocyte differentiation. |
title | Coupling growth arrest and adipocyte differentiation. |
title_full | Coupling growth arrest and adipocyte differentiation. |
title_fullStr | Coupling growth arrest and adipocyte differentiation. |
title_full_unstemmed | Coupling growth arrest and adipocyte differentiation. |
title_short | Coupling growth arrest and adipocyte differentiation. |
title_sort | coupling growth arrest and adipocyte differentiation. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567619/ https://www.ncbi.nlm.nih.gov/pubmed/2647477 |
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