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Inhalation toxicology and carcinogenicity of 1,3-butadiene in B6C3F1 mice following 65 weeks of exposure.
1,3-Butadiene, a large-production volume chemical used mainly in the manufacture of synthetic rubber, was found to induce multiple-organ carcinogenicity in male and female B6C3F1 mice at exposure concentrations (625 and 1250 ppm) equivalent to and below the OSHA standard of 1000 ppm. Since this stud...
Autores principales: | Melnick, R L, Huff, J E, Roycroft, J H, Chou, B J, Miller, R A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1990
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567751/ https://www.ncbi.nlm.nih.gov/pubmed/2401263 |
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