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Genetic analysis of the K-rev-1 transformation-suppressor gene.
Flat revertants with reduced malignancy in vivo can be isolated from Kirsten sarcoma virus-transformed NIH 3T3 cells (DT line) following transfection with a normal human fibroblast cDNA expression library. We have recovered from one such revertant a 1.8-kb cDNA clone, K-rev-1, that exhibits an activ...
Autores principales: | Kitayama, H, Matsuzaki, T, Sugimoto, Y, Ikawa, Y, Noda, M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1991
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568041/ https://www.ncbi.nlm.nih.gov/pubmed/1773804 |
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