Cargando…
ras activation in human tumors and in animal model systems.
Environmental agents such as radiation and chemicals are known to cause genetic damage. Alterations in a limited set of cellular genes called proto-oncogenes lead to unregulated proliferation and differentiation. We have studied the role of the ras gene family in carcinogenesis using two different a...
Autores principales: | Corominas, M, Sloan, S R, Leon, J, Kamino, H, Newcomb, E W, Pellicer, A |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
1991
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568045/ https://www.ncbi.nlm.nih.gov/pubmed/1773791 |
Ejemplares similares
-
Radiation and chemical activation of ras oncogenes in different mouse strains.
por: Newcomb, E W, et al.
Publicado: (1989) -
R-RAS2 overexpression in tumors of the human central nervous system
por: Gutierrez-Erlandsson, Sylvia, et al.
Publicado: (2013) -
The human Rgr oncogene is overexpressed in T cell malignancies and induces transformation by acting as a GEF for Ras and Ral
por: Osei-Sarfo, Kwame, et al.
Publicado: (2011) -
RasGRP3, a Ras activator, contributes to signaling and the tumorigenic phenotype in human melanoma
por: Yang, Dazhi, et al.
Publicado: (2011) -
In TCR-Stimulated T-cells, N-ras Regulates Specific Genes and Signal Transduction Pathways
por: Lynch, Stephen J., et al.
Publicado: (2013)