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Nonmutagenic mechanisms in carcinogenesis: role of protein kinase C in signal transduction and growth control.
There is accumulating evidence that the multistage carcinogenic process is associated with the progressive acquisition of mutations in cellular proto-oncogenes and in growth-suppressor genes. At the same time, several types of evidence indicate that nongenotoxic agents and epigenetic events also pla...
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| Formato: | Texto |
| Lenguaje: | English |
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1991
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568047/ https://www.ncbi.nlm.nih.gov/pubmed/1773790 |