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Multiple activation pathways of benzene leading to products with varying genotoxic characteristics.
Benzene and 13 potential metabolites were investigated for genotoxicity in Salmonella typhimurium and V79 Chinese hamster cells. In the presence of NADPH-fortified hepatic postmitochondrial fraction (S9 mix), benzene reverted his- S. typhimurium strains. The effect was strongest in strain TA1535. Am...
Autores principales: | Glatt, H, Padykula, R, Berchtold, G A, Ludewig, G, Platt, K L, Klein, J, Oesch, F |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1989
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568107/ https://www.ncbi.nlm.nih.gov/pubmed/2676505 |
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