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Chromatographic and spectrophotometric characterization of adducts formed during the reaction of trans,trans-muconaldehyde with 14C-deoxyguanosine 5'-phosphate.
Mice liver microsomes oxidatively open the benzene ring to form trans,trans-muconaldehyde, a hematotoxic unsaturated aldehyde. In the present studies, 4.5 mumole trans,trans-muconaldehyde was reacted with 14C-2'deoxyguanosine 5'-phosphate in phosphate buffer. Products were separated by hig...
Autores principales: | Latriano, L, Witz, G, Goldstein, B D, Jeffrey, A M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1989
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568139/ https://www.ncbi.nlm.nih.gov/pubmed/2792045 |
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