Quantitative studies on the in vitro metabolic activation of dimethylnitrosamine by rat liver postmitochondrial supernatant.

The metabolic activation of dimethylnitrosamine (DMN) to mutagenic and/or cytotoxic intermediates in vitro has been characterized and the relationship between DMN demethylase and ethoxyresorufin-O-deethylase (EROD) or ethylmorphine-N-demethylase (EMND) has been evaluated. A mammalian assay system wh...

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Detalles Bibliográficos
Autores principales: Doolittle, D J, Goodman, J I
Formato: Texto
Lenguaje:English
Publicado: 1984
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568286/
https://www.ncbi.nlm.nih.gov/pubmed/6499815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568286/
https://www.ncbi.nlm.nih.gov/pubmed/6499815

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