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Bleomycin-induced lung injury in the rat: effects of the platelet-activating factor (PAF) receptor antagonist BN 52021 and platelet depletion.

Bleomycin is a highly effective antitumor agent, but pulmonary toxicity, characterized by an acute inflammatory reaction and associated pulmonary edema, limits clinical use of the drug. Platelets and platelet-activating factor (PAF), a membrane-derived phospholipid, have been implicated in the mecha...

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Detalles Bibliográficos
Autores principales:	Evans, T W, McAnulty, R J, Rogers, D F, Chung, K F, Barnes, P J, Laurent, G J
Formato:	Texto
Lenguaje:	English
Publicado:	1990
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568314/ https://www.ncbi.nlm.nih.gov/pubmed/1696541

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