Estrogen receptors and breast cancer.

Estrogen receptors have been assayed in a series of primary breast cancers from postmenopausal women; 59% of which were estrogen-receptor positive. These patients survived for a significantly longer period of time than those whose tumors were estrogen-receptor negative. The effect of estrogen-recept...

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Detalles Bibliográficos
Autores principales: Nicholson, R I, Griffiths, K, Blamey, R W, Bishop, H M, Haybittle, J L
Formato: Texto
Lenguaje:English
Publicado: 1981
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568441/
https://www.ncbi.nlm.nih.gov/pubmed/7238443
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author Nicholson, R I
Griffiths, K
Blamey, R W
Bishop, H M
Haybittle, J L
author_facet Nicholson, R I
Griffiths, K
Blamey, R W
Bishop, H M
Haybittle, J L
author_sort Nicholson, R I
collection PubMed
description Estrogen receptors have been assayed in a series of primary breast cancers from postmenopausal women; 59% of which were estrogen-receptor positive. These patients survived for a significantly longer period of time than those whose tumors were estrogen-receptor negative. The effect of estrogen-receptor status was only seen (and then markedly accentuated) in patients who had lymph-node invasion at the time of mastectomy. Such determinations also appear to be of value in preselecting those patients who, on recurrence, will benefit from tamoxifen therapy.
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spelling pubmed-15684412006-09-19 Estrogen receptors and breast cancer. Nicholson, R I Griffiths, K Blamey, R W Bishop, H M Haybittle, J L Environ Health Perspect Research Article Estrogen receptors have been assayed in a series of primary breast cancers from postmenopausal women; 59% of which were estrogen-receptor positive. These patients survived for a significantly longer period of time than those whose tumors were estrogen-receptor negative. The effect of estrogen-receptor status was only seen (and then markedly accentuated) in patients who had lymph-node invasion at the time of mastectomy. Such determinations also appear to be of value in preselecting those patients who, on recurrence, will benefit from tamoxifen therapy. 1981-04 /pmc/articles/PMC1568441/ /pubmed/7238443 Text en
spellingShingle Research Article
Nicholson, R I
Griffiths, K
Blamey, R W
Bishop, H M
Haybittle, J L
Estrogen receptors and breast cancer.
title Estrogen receptors and breast cancer.
title_full Estrogen receptors and breast cancer.
title_fullStr Estrogen receptors and breast cancer.
title_full_unstemmed Estrogen receptors and breast cancer.
title_short Estrogen receptors and breast cancer.
title_sort estrogen receptors and breast cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568441/
https://www.ncbi.nlm.nih.gov/pubmed/7238443
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AT griffithsk estrogenreceptorsandbreastcancer
AT blameyrw estrogenreceptorsandbreastcancer
AT bishophm estrogenreceptorsandbreastcancer
AT haybittlejl estrogenreceptorsandbreastcancer

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