Free radical-mediated activation of hydrazine derivatives.

Hydrazines are known to undergo oxidative activation in several enzymatic systems in vitro. Free radicals or carbonium ions have been proposed as active intermediates during such activation. The toxic effects elicited by hydrazines have also been linked to free radical-mediated activation. In this r...

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Detalles Bibliográficos
Autores principales: Kalyanaraman, B, Sinha, B K
Formato: Texto
Lenguaje:English
Publicado: 1985
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568606/
https://www.ncbi.nlm.nih.gov/pubmed/3007088
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author Kalyanaraman, B
Sinha, B K
author_facet Kalyanaraman, B
Sinha, B K
author_sort Kalyanaraman, B
collection PubMed
description Hydrazines are known to undergo oxidative activation in several enzymatic systems in vitro. Free radicals or carbonium ions have been proposed as active intermediates during such activation. The toxic effects elicited by hydrazines have also been linked to free radical-mediated activation. In this report, we have reviewed the identification of organic free radicals from hydrazines by direct ESR and ESR-spin trapping.
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spelling pubmed-15686062006-09-18 Free radical-mediated activation of hydrazine derivatives. Kalyanaraman, B Sinha, B K Environ Health Perspect Research Article Hydrazines are known to undergo oxidative activation in several enzymatic systems in vitro. Free radicals or carbonium ions have been proposed as active intermediates during such activation. The toxic effects elicited by hydrazines have also been linked to free radical-mediated activation. In this report, we have reviewed the identification of organic free radicals from hydrazines by direct ESR and ESR-spin trapping. 1985-12 /pmc/articles/PMC1568606/ /pubmed/3007088 Text en
spellingShingle Research Article
Kalyanaraman, B
Sinha, B K
Free radical-mediated activation of hydrazine derivatives.
title Free radical-mediated activation of hydrazine derivatives.
title_full Free radical-mediated activation of hydrazine derivatives.
title_fullStr Free radical-mediated activation of hydrazine derivatives.
title_full_unstemmed Free radical-mediated activation of hydrazine derivatives.
title_short Free radical-mediated activation of hydrazine derivatives.
title_sort free radical-mediated activation of hydrazine derivatives.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568606/
https://www.ncbi.nlm.nih.gov/pubmed/3007088
work_keys_str_mv AT kalyanaramanb freeradicalmediatedactivationofhydrazinederivatives
AT sinhabk freeradicalmediatedactivationofhydrazinederivatives

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