Physiological aspects of free-radical reactions.

Enzymes which catalyze the formation of free radicals in vitro will catalyze similar reactions in vivo. We believe that the formation of some kinds of free radicals has definite physiological meanings in metabolism. In this sense, the enzymes forming such free radicals are concluded to be in evoluti...

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Detalles Bibliográficos
Autores principales: Yamazaki, I, Tamura, M, Nakajima, R, Nakamura, M
Formato: Texto
Lenguaje:English
Publicado: 1985
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568608/
https://www.ncbi.nlm.nih.gov/pubmed/3007098
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author Yamazaki, I
Tamura, M
Nakajima, R
Nakamura, M
author_facet Yamazaki, I
Tamura, M
Nakajima, R
Nakamura, M
author_sort Yamazaki, I
collection PubMed
description Enzymes which catalyze the formation of free radicals in vitro will catalyze similar reactions in vivo. We believe that the formation of some kinds of free radicals has definite physiological meanings in metabolism. In this sense, the enzymes forming such free radicals are concluded to be in evolutionally advanced states. Elaborated structure and function of enzymes such as horseradish peroxidase and microsomal flavoproteins support the idea. Deleterious and side reactions caused by free radicals are assumed to be minimized in vivo by localizing the reactions, but this assumption should be verified by future studies.
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spelling pubmed-15686082006-09-18 Physiological aspects of free-radical reactions. Yamazaki, I Tamura, M Nakajima, R Nakamura, M Environ Health Perspect Research Article Enzymes which catalyze the formation of free radicals in vitro will catalyze similar reactions in vivo. We believe that the formation of some kinds of free radicals has definite physiological meanings in metabolism. In this sense, the enzymes forming such free radicals are concluded to be in evolutionally advanced states. Elaborated structure and function of enzymes such as horseradish peroxidase and microsomal flavoproteins support the idea. Deleterious and side reactions caused by free radicals are assumed to be minimized in vivo by localizing the reactions, but this assumption should be verified by future studies. 1985-12 /pmc/articles/PMC1568608/ /pubmed/3007098 Text en
spellingShingle Research Article
Yamazaki, I
Tamura, M
Nakajima, R
Nakamura, M
Physiological aspects of free-radical reactions.
title Physiological aspects of free-radical reactions.
title_full Physiological aspects of free-radical reactions.
title_fullStr Physiological aspects of free-radical reactions.
title_full_unstemmed Physiological aspects of free-radical reactions.
title_short Physiological aspects of free-radical reactions.
title_sort physiological aspects of free-radical reactions.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568608/
https://www.ncbi.nlm.nih.gov/pubmed/3007098
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AT tamuram physiologicalaspectsoffreeradicalreactions
AT nakajimar physiologicalaspectsoffreeradicalreactions
AT nakamuram physiologicalaspectsoffreeradicalreactions

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