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Free-radical metabolites of acetaminophen and a dimethylated derivative.
The oxidation of acetaminophen (4'-hydroxyacetanilide) to the corresponding N-acetyl-p-benzoquinone imines by plant and mammalian peroxidases is discussed. The acetaminophen free radical (N-acetyl-4-aminophenoxyl) has been reported as an intermediate. It is very reactive and forms melanin-like...
Autores principales: | Fischer, V, West, P R, Harman, L S, Mason, R P |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
1985
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568611/ https://www.ncbi.nlm.nih.gov/pubmed/3007084 |
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