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Formation and repair of psoralen-DNA adducts and pyrimidine dimers in human DNA and chromatin.

DNA damage and repair in human cells exposed to ultraviolet light (254 nm) or to psoralen derivatives plus 360 nm light were compared by means of a variety of analytic techniques. The two kinds of damage show considerable structural similarity; both involve cyclobutyl bonds to 5,6 positions of pyrim...

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Detalles Bibliográficos
Autores principales: Cleaver, J E, Killpack, S, Gruenert, D C
Formato: Texto
Lenguaje:English
Publicado: 1985
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568663/
https://www.ncbi.nlm.nih.gov/pubmed/3002774