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In vivo formation and persistence of modified nucleosides resulting from alkylating agents.
Alkylating agents are ubiquitous in the human environment and are continuously synthesized in vivo. Although many classes exist, interest has been focused on the N-nitroso compounds, since many are mutagens for bacteria, phage, and cells, and carcinogens for mammals. In contrast to aromatic amines a...
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Formato: | Texto |
Lenguaje: | English |
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1985
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568687/ https://www.ncbi.nlm.nih.gov/pubmed/4085444 |