Dose-response analysis in animal studies: prediction of human responses.

An animal bioassay has been used to evaluate a series of airborne chemicals for their sensory irritating properties to the upper respiratory tract. Teh results obtained can be used to rank their potency. An attempt has been made to predict "safe" levels of exposure for humans on the basis...

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Detalles Bibliográficos
Autor principal: Alarie, Y
Formato: Texto
Lenguaje:English
Publicado: 1981
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568799/
https://www.ncbi.nlm.nih.gov/pubmed/7333265
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author Alarie, Y
author_facet Alarie, Y
author_sort Alarie, Y
collection PubMed
description An animal bioassay has been used to evaluate a series of airborne chemicals for their sensory irritating properties to the upper respiratory tract. Teh results obtained can be used to rank their potency. An attempt has been made to predict "safe" levels of exposure for humans on the basis of this short-term assay. A good correlation was obtained between the predicted "safe" levels of exposure and current Threshold Limit Values established for industrial exposures.
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spelling pubmed-15687992006-09-19 Dose-response analysis in animal studies: prediction of human responses. Alarie, Y Environ Health Perspect Research Article An animal bioassay has been used to evaluate a series of airborne chemicals for their sensory irritating properties to the upper respiratory tract. Teh results obtained can be used to rank their potency. An attempt has been made to predict "safe" levels of exposure for humans on the basis of this short-term assay. A good correlation was obtained between the predicted "safe" levels of exposure and current Threshold Limit Values established for industrial exposures. 1981-12 /pmc/articles/PMC1568799/ /pubmed/7333265 Text en
spellingShingle Research Article
Alarie, Y
Dose-response analysis in animal studies: prediction of human responses.
title Dose-response analysis in animal studies: prediction of human responses.
title_full Dose-response analysis in animal studies: prediction of human responses.
title_fullStr Dose-response analysis in animal studies: prediction of human responses.
title_full_unstemmed Dose-response analysis in animal studies: prediction of human responses.
title_short Dose-response analysis in animal studies: prediction of human responses.
title_sort dose-response analysis in animal studies: prediction of human responses.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568799/
https://www.ncbi.nlm.nih.gov/pubmed/7333265
work_keys_str_mv AT alariey doseresponseanalysisinanimalstudiespredictionofhumanresponses

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