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Chemistry of carcinogenic metals.

The periodic distribution of known and suspected carcinogenic metal ions is described, and the chemical behavior of various types of metal ions is explained in terms of the general theory of hard and soft acids and bases. The chelate effect is elucidated, and the relatively high stability of metal c...

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Detalles Bibliográficos
Autor principal: Martell, A E
Formato: Texto
Lenguaje:English
Publicado: 1981
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568828/
https://www.ncbi.nlm.nih.gov/pubmed/6791915
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author Martell, A E
author_facet Martell, A E
author_sort Martell, A E
collection PubMed
description The periodic distribution of known and suspected carcinogenic metal ions is described, and the chemical behavior of various types of metal ions is explained in terms of the general theory of hard and soft acids and bases. The chelate effect is elucidated, and the relatively high stability of metal chelates in very dilute solutions is discussed. The concepts employed for the chelate effect are extended to explain the high stabilities of macrocyclic and cryptate complexes. Procedures for the use of equilibrium data to determine the speciation of metal ions and complexes under varying solution conditions are described. Methods for assessing the interferences by hydrogen ion, competing metal ions, hydrolysis, and precipitation are explained, and are applied to systems containing iron(III) chelates of fourteen chelating agents designed for effective binding of the ferric ion. The donor groups available for the building up of multidentate ligands are presented, and the ways in which they may be combined to achieve high affinity and selectivity for certain types of metal ions are explained.
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spelling pubmed-15688282006-09-19 Chemistry of carcinogenic metals. Martell, A E Environ Health Perspect Research Article The periodic distribution of known and suspected carcinogenic metal ions is described, and the chemical behavior of various types of metal ions is explained in terms of the general theory of hard and soft acids and bases. The chelate effect is elucidated, and the relatively high stability of metal chelates in very dilute solutions is discussed. The concepts employed for the chelate effect are extended to explain the high stabilities of macrocyclic and cryptate complexes. Procedures for the use of equilibrium data to determine the speciation of metal ions and complexes under varying solution conditions are described. Methods for assessing the interferences by hydrogen ion, competing metal ions, hydrolysis, and precipitation are explained, and are applied to systems containing iron(III) chelates of fourteen chelating agents designed for effective binding of the ferric ion. The donor groups available for the building up of multidentate ligands are presented, and the ways in which they may be combined to achieve high affinity and selectivity for certain types of metal ions are explained. 1981-08 /pmc/articles/PMC1568828/ /pubmed/6791915 Text en
spellingShingle Research Article
Martell, A E
Chemistry of carcinogenic metals.
title Chemistry of carcinogenic metals.
title_full Chemistry of carcinogenic metals.
title_fullStr Chemistry of carcinogenic metals.
title_full_unstemmed Chemistry of carcinogenic metals.
title_short Chemistry of carcinogenic metals.
title_sort chemistry of carcinogenic metals.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1568828/
https://www.ncbi.nlm.nih.gov/pubmed/6791915
work_keys_str_mv AT martellae chemistryofcarcinogenicmetals