Hepatic effects of a phthalate ester plasticizer leached from poly(vinyl chloride) blood bags following transfusion.

The effects of di(2-ethylhexyl) phthalate (DEHP) on hepatic function and histology were evaluated in the rhesus monkey undergoing platelet and plasma transfusion. The average cumulative amount infused in one year is comparable to that received by patients who undergo chronic transfusion. Abnormaliti...

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Detalles Bibliográficos
Autores principales: Kevy, S V, Jacobson, M S
Formato: Texto
Lenguaje:English
Publicado: 1982
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569017/
https://www.ncbi.nlm.nih.gov/pubmed/7140697
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author Kevy, S V
Jacobson, M S
author_facet Kevy, S V
Jacobson, M S
author_sort Kevy, S V
collection PubMed
description The effects of di(2-ethylhexyl) phthalate (DEHP) on hepatic function and histology were evaluated in the rhesus monkey undergoing platelet and plasma transfusion. The average cumulative amount infused in one year is comparable to that received by patients who undergo chronic transfusion. Abnormalities in hepatic scan and BSP kinetics persisted for up to 26 months after transfusion, as did histologic abnormalities. Patients undergoing maintenance hemodialysis receive a yearly dose of DEHP which is 10-20 times that which produced hepatotoxicity in the transfused rhesus.
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spelling pubmed-15690172006-09-19 Hepatic effects of a phthalate ester plasticizer leached from poly(vinyl chloride) blood bags following transfusion. Kevy, S V Jacobson, M S Environ Health Perspect Research Article The effects of di(2-ethylhexyl) phthalate (DEHP) on hepatic function and histology were evaluated in the rhesus monkey undergoing platelet and plasma transfusion. The average cumulative amount infused in one year is comparable to that received by patients who undergo chronic transfusion. Abnormalities in hepatic scan and BSP kinetics persisted for up to 26 months after transfusion, as did histologic abnormalities. Patients undergoing maintenance hemodialysis receive a yearly dose of DEHP which is 10-20 times that which produced hepatotoxicity in the transfused rhesus. 1982-11 /pmc/articles/PMC1569017/ /pubmed/7140697 Text en
spellingShingle Research Article
Kevy, S V
Jacobson, M S
Hepatic effects of a phthalate ester plasticizer leached from poly(vinyl chloride) blood bags following transfusion.
title Hepatic effects of a phthalate ester plasticizer leached from poly(vinyl chloride) blood bags following transfusion.
title_full Hepatic effects of a phthalate ester plasticizer leached from poly(vinyl chloride) blood bags following transfusion.
title_fullStr Hepatic effects of a phthalate ester plasticizer leached from poly(vinyl chloride) blood bags following transfusion.
title_full_unstemmed Hepatic effects of a phthalate ester plasticizer leached from poly(vinyl chloride) blood bags following transfusion.
title_short Hepatic effects of a phthalate ester plasticizer leached from poly(vinyl chloride) blood bags following transfusion.
title_sort hepatic effects of a phthalate ester plasticizer leached from poly(vinyl chloride) blood bags following transfusion.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569017/
https://www.ncbi.nlm.nih.gov/pubmed/7140697
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AT jacobsonms hepaticeffectsofaphthalateesterplasticizerleachedfrompolyvinylchloridebloodbagsfollowingtransfusion

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