Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer.

Consistent with the proposed precursor relationship of GGTase-positive foci to hepatocarcinogenesis, the induction of foci by DBN was associated with the induction of hyperplastic nodules and hepatocellular carcinoma and the concurrent administration of sodium saccharin in the diet with DBN in the d...

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Detalles Bibliográficos
Autores principales: Pereira, M A, Herren, S L, Britt, A L
Formato: Texto
Lenguaje:English
Publicado: 1983
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569209/
https://www.ncbi.nlm.nih.gov/pubmed/6135608
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author Pereira, M A
Herren, S L
Britt, A L
author_facet Pereira, M A
Herren, S L
Britt, A L
author_sort Pereira, M A
collection PubMed
description Consistent with the proposed precursor relationship of GGTase-positive foci to hepatocarcinogenesis, the induction of foci by DBN was associated with the induction of hyperplastic nodules and hepatocellular carcinoma and the concurrent administration of sodium saccharin in the diet with DBN in the drinking water increased the tumorigenic response in the liver to DBN.
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spelling pubmed-15692092006-09-18 Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer. Pereira, M A Herren, S L Britt, A L Environ Health Perspect Research Article Consistent with the proposed precursor relationship of GGTase-positive foci to hepatocarcinogenesis, the induction of foci by DBN was associated with the induction of hyperplastic nodules and hepatocellular carcinoma and the concurrent administration of sodium saccharin in the diet with DBN in the drinking water increased the tumorigenic response in the liver to DBN. 1983-04 /pmc/articles/PMC1569209/ /pubmed/6135608 Text en
spellingShingle Research Article
Pereira, M A
Herren, S L
Britt, A L
Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer.
title Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer.
title_full Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer.
title_fullStr Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer.
title_full_unstemmed Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer.
title_short Effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer.
title_sort effect of dibutylnitrosamine and saccharin on glutamyl transpeptidase-positive foci and liver cancer.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569209/
https://www.ncbi.nlm.nih.gov/pubmed/6135608
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AT herrensl effectofdibutylnitrosamineandsaccharinonglutamyltranspeptidasepositivefociandlivercancer
AT brittal effectofdibutylnitrosamineandsaccharinonglutamyltranspeptidasepositivefociandlivercancer

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