Interactions of asbestos-activated macrophages with an experimental fibrosarcoma.

Supernatants from in vivo asbestos-activated macrophages failed to show any cytostatic activity against a syngeneic fibrosarcoma cell line in vitro. UICC chrysotile-induced peritoneal exudate cells also failed to demonstrate any growth inhibitory effect on the same cells in Winn assays of tumor grow...

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Detalles Bibliográficos
Autores principales: Donaldson, K, Davis, J M, Ewing, A, James, K
Formato: Texto
Lenguaje:English
Publicado: 1983
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569285/
https://www.ncbi.nlm.nih.gov/pubmed/6315388
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author Donaldson, K
Davis, J M
Ewing, A
James, K
author_facet Donaldson, K
Davis, J M
Ewing, A
James, K
author_sort Donaldson, K
collection PubMed
description Supernatants from in vivo asbestos-activated macrophages failed to show any cytostatic activity against a syngeneic fibrosarcoma cell line in vitro. UICC chrysotile-induced peritoneal exudate cells also failed to demonstrate any growth inhibitory effect on the same cells in Winn assays of tumor growth. Mixing UICC crocidolite with inoculated tumor cells resulted in a dose-dependent inhibition of tumor growth; this could, however, be explained by a direct cytostatic effect on the tumor cells of high doses of crocidolite, which was observed in vitro.
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spelling pubmed-15692852006-09-18 Interactions of asbestos-activated macrophages with an experimental fibrosarcoma. Donaldson, K Davis, J M Ewing, A James, K Environ Health Perspect Research Article Supernatants from in vivo asbestos-activated macrophages failed to show any cytostatic activity against a syngeneic fibrosarcoma cell line in vitro. UICC chrysotile-induced peritoneal exudate cells also failed to demonstrate any growth inhibitory effect on the same cells in Winn assays of tumor growth. Mixing UICC crocidolite with inoculated tumor cells resulted in a dose-dependent inhibition of tumor growth; this could, however, be explained by a direct cytostatic effect on the tumor cells of high doses of crocidolite, which was observed in vitro. 1983-09 /pmc/articles/PMC1569285/ /pubmed/6315388 Text en
spellingShingle Research Article
Donaldson, K
Davis, J M
Ewing, A
James, K
Interactions of asbestos-activated macrophages with an experimental fibrosarcoma.
title Interactions of asbestos-activated macrophages with an experimental fibrosarcoma.
title_full Interactions of asbestos-activated macrophages with an experimental fibrosarcoma.
title_fullStr Interactions of asbestos-activated macrophages with an experimental fibrosarcoma.
title_full_unstemmed Interactions of asbestos-activated macrophages with an experimental fibrosarcoma.
title_short Interactions of asbestos-activated macrophages with an experimental fibrosarcoma.
title_sort interactions of asbestos-activated macrophages with an experimental fibrosarcoma.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569285/
https://www.ncbi.nlm.nih.gov/pubmed/6315388
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AT jamesk interactionsofasbestosactivatedmacrophageswithanexperimentalfibrosarcoma

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