Effects of chrysotile co-exposure on BaP binding in normal human fibroblasts.

The effects of chrysotile and benzo(a)pyrene (BaP) co-exposure on uptake, metabolism and BaP binding to nucleic acids were investigated in normal human fibroblasts. A significant enhancement in these parameters was found when co-exposure was carried out under serum-free conditions. In the presence o...

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Detalles Bibliográficos
Autores principales: Chang, M J, Singh, N P, Hart, R W
Formato: Texto
Lenguaje:English
Publicado: 1983
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569294/
https://www.ncbi.nlm.nih.gov/pubmed/6315365
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author Chang, M J
Singh, N P
Hart, R W
author_facet Chang, M J
Singh, N P
Hart, R W
author_sort Chang, M J
collection PubMed
description The effects of chrysotile and benzo(a)pyrene (BaP) co-exposure on uptake, metabolism and BaP binding to nucleic acids were investigated in normal human fibroblasts. A significant enhancement in these parameters was found when co-exposure was carried out under serum-free conditions. In the presence of serum, only a slight enhancement of BaP uptake was detected, while metabolism and binding to nucleic acids were not affected over the 8-hr incubation period studied.
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spelling pubmed-15692942006-09-18 Effects of chrysotile co-exposure on BaP binding in normal human fibroblasts. Chang, M J Singh, N P Hart, R W Environ Health Perspect Research Article The effects of chrysotile and benzo(a)pyrene (BaP) co-exposure on uptake, metabolism and BaP binding to nucleic acids were investigated in normal human fibroblasts. A significant enhancement in these parameters was found when co-exposure was carried out under serum-free conditions. In the presence of serum, only a slight enhancement of BaP uptake was detected, while metabolism and binding to nucleic acids were not affected over the 8-hr incubation period studied. 1983-09 /pmc/articles/PMC1569294/ /pubmed/6315365 Text en
spellingShingle Research Article
Chang, M J
Singh, N P
Hart, R W
Effects of chrysotile co-exposure on BaP binding in normal human fibroblasts.
title Effects of chrysotile co-exposure on BaP binding in normal human fibroblasts.
title_full Effects of chrysotile co-exposure on BaP binding in normal human fibroblasts.
title_fullStr Effects of chrysotile co-exposure on BaP binding in normal human fibroblasts.
title_full_unstemmed Effects of chrysotile co-exposure on BaP binding in normal human fibroblasts.
title_short Effects of chrysotile co-exposure on BaP binding in normal human fibroblasts.
title_sort effects of chrysotile co-exposure on bap binding in normal human fibroblasts.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569294/
https://www.ncbi.nlm.nih.gov/pubmed/6315365
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