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Measurement and analysis of chemically changed mineral fibers after experiments in vitro and in vivo.

Asbestos, as well as other natural and man-made mineral fibers used for in vitro and in vivo experiments, must be described and defined physically and chemically as exactly as possible before any application. The interactions of fibers with the physical, chemical (air, water, etc.) and biological (c...

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Detalles Bibliográficos
Autor principal: Spurny, K R
Formato: Texto
Lenguaje:English
Publicado: 1983
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569303/
https://www.ncbi.nlm.nih.gov/pubmed/6315377
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author Spurny, K R
author_facet Spurny, K R
author_sort Spurny, K R
collection PubMed
description Asbestos, as well as other natural and man-made mineral fibers used for in vitro and in vivo experiments, must be described and defined physically and chemically as exactly as possible before any application. The interactions of fibers with the physical, chemical (air, water, etc.) and biological (cells, tissues, etc.) environments cause important changes in fiber chemistry and crystalline structure. Also, these should be detected as precisely as possible after each experiment. Our recent investigations dealt with the development of a complex analytical system for such measurements and with some applications of these analytical procedures for fibrous material sampled in the environment and from biological materials. Chemical and physical microanalyses of asbestos and glass fibers obtained by environmental sampling (air, water) and from human and animal tissue have shown chemical and crystalline changes in these particles. Scanning electron microscopy, electron microprobe analysis and mass spectrometry analysis were used in these investigations. A partial or total leakage of elements could be observed. The leakage of elements in fibers is of a statistical nature. Some fibers remained chemically unchanged; in some fibers some elements were partially leached; and in some fibers the majority of metallic elements were leached. The potential meaning of this effect is also discussed.
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spelling pubmed-15693032006-09-18 Measurement and analysis of chemically changed mineral fibers after experiments in vitro and in vivo. Spurny, K R Environ Health Perspect Research Article Asbestos, as well as other natural and man-made mineral fibers used for in vitro and in vivo experiments, must be described and defined physically and chemically as exactly as possible before any application. The interactions of fibers with the physical, chemical (air, water, etc.) and biological (cells, tissues, etc.) environments cause important changes in fiber chemistry and crystalline structure. Also, these should be detected as precisely as possible after each experiment. Our recent investigations dealt with the development of a complex analytical system for such measurements and with some applications of these analytical procedures for fibrous material sampled in the environment and from biological materials. Chemical and physical microanalyses of asbestos and glass fibers obtained by environmental sampling (air, water) and from human and animal tissue have shown chemical and crystalline changes in these particles. Scanning electron microscopy, electron microprobe analysis and mass spectrometry analysis were used in these investigations. A partial or total leakage of elements could be observed. The leakage of elements in fibers is of a statistical nature. Some fibers remained chemically unchanged; in some fibers some elements were partially leached; and in some fibers the majority of metallic elements were leached. The potential meaning of this effect is also discussed. 1983-09 /pmc/articles/PMC1569303/ /pubmed/6315377 Text en
spellingShingle Research Article
Spurny, K R
Measurement and analysis of chemically changed mineral fibers after experiments in vitro and in vivo.
title Measurement and analysis of chemically changed mineral fibers after experiments in vitro and in vivo.
title_full Measurement and analysis of chemically changed mineral fibers after experiments in vitro and in vivo.
title_fullStr Measurement and analysis of chemically changed mineral fibers after experiments in vitro and in vivo.
title_full_unstemmed Measurement and analysis of chemically changed mineral fibers after experiments in vitro and in vivo.
title_short Measurement and analysis of chemically changed mineral fibers after experiments in vitro and in vivo.
title_sort measurement and analysis of chemically changed mineral fibers after experiments in vitro and in vivo.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569303/
https://www.ncbi.nlm.nih.gov/pubmed/6315377
work_keys_str_mv AT spurnykr measurementandanalysisofchemicallychangedmineralfibersafterexperimentsinvitroandinvivo