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Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens
We previously reported evidence of West Nile virus (WNV) circulation in UK birds, probably introduced by migratory birds from overseas. We now demonstrate WNV-specific seroconversion in sentinel chickens raised on an English farm. Maternal neutralizing antibodies to WNV in hatchlings declined within...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569371/ https://www.ncbi.nlm.nih.gov/pubmed/16952307 http://dx.doi.org/10.1186/1743-422X-3-71 |
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author | Buckley, Alan Dawson, Alistair Gould, Ernest A |
author_facet | Buckley, Alan Dawson, Alistair Gould, Ernest A |
author_sort | Buckley, Alan |
collection | PubMed |
description | We previously reported evidence of West Nile virus (WNV) circulation in UK birds, probably introduced by migratory birds from overseas. We now demonstrate WNV-specific seroconversion in sentinel chickens raised on an English farm. Maternal neutralizing antibodies to WNV in hatchlings declined within three weeks. During the following months, healthy chickens developed WNV neutralizing antibodies that were confirmed by immunoblotting and indirect immunofluorescence tests using WNV antigens. The proportion of seropositive chickens was higher for WNV than for Usutu virus or Sindbis virus. Attempts to isolate infectious virus or to detect viral RNA in the sera, failed. |
format | Text |
id | pubmed-1569371 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-15693712006-09-16 Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens Buckley, Alan Dawson, Alistair Gould, Ernest A Virol J Short Report We previously reported evidence of West Nile virus (WNV) circulation in UK birds, probably introduced by migratory birds from overseas. We now demonstrate WNV-specific seroconversion in sentinel chickens raised on an English farm. Maternal neutralizing antibodies to WNV in hatchlings declined within three weeks. During the following months, healthy chickens developed WNV neutralizing antibodies that were confirmed by immunoblotting and indirect immunofluorescence tests using WNV antigens. The proportion of seropositive chickens was higher for WNV than for Usutu virus or Sindbis virus. Attempts to isolate infectious virus or to detect viral RNA in the sera, failed. BioMed Central 2006-09-04 /pmc/articles/PMC1569371/ /pubmed/16952307 http://dx.doi.org/10.1186/1743-422X-3-71 Text en Copyright © 2006 Buckley et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Report Buckley, Alan Dawson, Alistair Gould, Ernest A Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens |
title | Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens |
title_full | Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens |
title_fullStr | Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens |
title_full_unstemmed | Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens |
title_short | Detection of seroconversion to West Nile virus, Usutu virus and Sindbis virus in UK sentinel chickens |
title_sort | detection of seroconversion to west nile virus, usutu virus and sindbis virus in uk sentinel chickens |
topic | Short Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569371/ https://www.ncbi.nlm.nih.gov/pubmed/16952307 http://dx.doi.org/10.1186/1743-422X-3-71 |
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