Cargando…
Expression profiling of clonal lymphocyte cell cultures from Rett syndrome patients
BACKGROUND: More than 85% of Rett syndrome (RTT) patients have heterozygous mutations in the X-linked MECP2 gene which encodes methyl-CpG-binding protein 2, a transcriptional repressor that binds methylated CpG sites. Because MECP2 is subject to X chromosome inactivation (XCI), girls with RTT expres...
Autores principales: | Delgado, Ivan J, Kim, Dong Sun, Thatcher, Karen N, LaSalle, Janine M, Van den Veyver, Ignatia B |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1569822/ https://www.ncbi.nlm.nih.gov/pubmed/16859563 http://dx.doi.org/10.1186/1471-2350-7-61 |
Ejemplares similares
-
Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism
por: Swanberg, Susan E., et al.
Publicado: (2009) -
Investigation of modifier genes within copy number variations in Rett syndrome
por: Artuso, Rosangela, et al.
Publicado: (2011) -
Recent advances in prenatal genetic screening and testing
por: Van den Veyver, Ignatia B.
Publicado: (2016) -
Epigenetics in Prader-Willi Syndrome
por: Mendiola, Aron Judd P., et al.
Publicado: (2021) -
Sex disparate gut microbiome and metabolome perturbations precede disease progression in a mouse model of Rett syndrome
por: Neier, Kari, et al.
Publicado: (2021)