Exit from Arsenite-Induced Mitotic Arrest Is p53 Dependent

BACKGROUND: Arsenic is both a human carcinogen and a chemotherapeutic agent, but the mechanism of neither arsenic-induced carcinogenesis nor tumor selective cytotoxicity is clear. Using a model cell line in which p53 expression is regulated exogenously in a tetracycline-off system (TR9-7 cells), our...

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Detalles Bibliográficos
Autores principales: McNeely, Samuel C., Xu, Xiaogiang, Taylor, B. Frazier, Zacharias, Wolfgang, McCabe, Michael J., States, J. Christopher
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570045/
https://www.ncbi.nlm.nih.gov/pubmed/16966095
http://dx.doi.org/10.1289/ehp.8969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570045/
https://www.ncbi.nlm.nih.gov/pubmed/16966095
http://dx.doi.org/10.1289/ehp.8969

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