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FAT10, a gene up-regulated in various cancers, is cell-cycle regulated
BACKGROUND: FAT10 is a member of the ubiquitin-like-modifier family of proteins. Over-expression of the FAT10 gene was observed in the tumors of several epithelial cancers. High FAT10 expression was found to lead to increased chromosome instability via the reduction in the kinetochore localization o...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570338/ https://www.ncbi.nlm.nih.gov/pubmed/16959044 http://dx.doi.org/10.1186/1747-1028-1-20 |