Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression

The microtubule-associated protein tau (MAPT) is a pathological component of several neurodegenerative diseases and clinical dementias. Here, we have investigated the effects of a series of commercially available FDA-approved compounds and natural products on total tau protein levels using a cell-ba...

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Detalles Bibliográficos
Autores principales: Dickey, Chad A, Ash, Peter, Klosak, Natalia, Lee, Wing C, Petrucelli, Leonard, Hutton, Michael, Eckman, Christopher B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570347/
https://www.ncbi.nlm.nih.gov/pubmed/16930453
http://dx.doi.org/10.1186/1750-1326-1-6

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