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The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome

AIM: Once considered a problem of developed countries, obesity and obesity-related complications (such as metabolic syndrome) are rapidly spreading around the globe. The purpose of the present study was to investigate the use of a Cissus quadrangularis formulation in the management of metabolic synd...

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Autores principales: Oben, Julius, Kuate, Dieudonne, Agbor, Gabriel, Momo, Claudia, Talla, Xavio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570348/
https://www.ncbi.nlm.nih.gov/pubmed/16948861
http://dx.doi.org/10.1186/1476-511X-5-24
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author Oben, Julius
Kuate, Dieudonne
Agbor, Gabriel
Momo, Claudia
Talla, Xavio
author_facet Oben, Julius
Kuate, Dieudonne
Agbor, Gabriel
Momo, Claudia
Talla, Xavio
author_sort Oben, Julius
collection PubMed
description AIM: Once considered a problem of developed countries, obesity and obesity-related complications (such as metabolic syndrome) are rapidly spreading around the globe. The purpose of the present study was to investigate the use of a Cissus quadrangularis formulation in the management of metabolic syndrome, particularly weight loss and central obesity. METHODS: The study was a randomized, double-blind, placebo-controlled design involving 123 overweight and obese persons (47.2% male; 52.8% female; ages 19–50). The 92 obese (BMI >30) participants were randomized into three groups; placebo, formulation/no diet, and formulation/diet (2100–2200 calories/day). The 31 overweight participants (BMI = 25–29) formed a fourth (no diet) treatment group. All participants received two daily doses of the formulation or placebo and remained on a normal or calorie-controlled diet for 8 weeks. RESULTS: At the end of the trial period, statistically significant net reductions in weight and central obesity, as well as in fasting blood glucose, total cholesterol, LDL-cholesterol, triglycerides, and C-reactive protein were observed in participants who received the formulation, regardless of diet. CONCLUSION: Cissus quadrangularis formulation appears to be useful in the management of weight loss and metabolic syndrome.
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spelling pubmed-15703482006-09-20 The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome Oben, Julius Kuate, Dieudonne Agbor, Gabriel Momo, Claudia Talla, Xavio Lipids Health Dis Research AIM: Once considered a problem of developed countries, obesity and obesity-related complications (such as metabolic syndrome) are rapidly spreading around the globe. The purpose of the present study was to investigate the use of a Cissus quadrangularis formulation in the management of metabolic syndrome, particularly weight loss and central obesity. METHODS: The study was a randomized, double-blind, placebo-controlled design involving 123 overweight and obese persons (47.2% male; 52.8% female; ages 19–50). The 92 obese (BMI >30) participants were randomized into three groups; placebo, formulation/no diet, and formulation/diet (2100–2200 calories/day). The 31 overweight participants (BMI = 25–29) formed a fourth (no diet) treatment group. All participants received two daily doses of the formulation or placebo and remained on a normal or calorie-controlled diet for 8 weeks. RESULTS: At the end of the trial period, statistically significant net reductions in weight and central obesity, as well as in fasting blood glucose, total cholesterol, LDL-cholesterol, triglycerides, and C-reactive protein were observed in participants who received the formulation, regardless of diet. CONCLUSION: Cissus quadrangularis formulation appears to be useful in the management of weight loss and metabolic syndrome. BioMed Central 2006-09-02 /pmc/articles/PMC1570348/ /pubmed/16948861 http://dx.doi.org/10.1186/1476-511X-5-24 Text en Copyright © 2006 Oben et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Oben, Julius
Kuate, Dieudonne
Agbor, Gabriel
Momo, Claudia
Talla, Xavio
The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome
title The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome
title_full The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome
title_fullStr The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome
title_full_unstemmed The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome
title_short The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome
title_sort use of a cissus quadrangularis formulation in the management of weight loss and metabolic syndrome
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570348/
https://www.ncbi.nlm.nih.gov/pubmed/16948861
http://dx.doi.org/10.1186/1476-511X-5-24
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