Cargando…
Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome
The etiology of BMS remains unknown. Role of various cytokines has been implicated in the development of BMS. The aim of this study was to evaluate levels of salivary IL-2 and IL-6 in patients with BMS, compared with age-matched healthy volunteers (control group). Whole saliva from 30 patients with...
Autores principales: | , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570384/ https://www.ncbi.nlm.nih.gov/pubmed/16864905 http://dx.doi.org/10.1155/MI/2006/54632 |
_version_ | 1782130262373564416 |
---|---|
author | Simčić, Daria Pezelj-Ribarić, Sonja Gržić, Renata Horvat, Jelena Brumini, Gordana Muhvić-Urek, Miranda |
author_facet | Simčić, Daria Pezelj-Ribarić, Sonja Gržić, Renata Horvat, Jelena Brumini, Gordana Muhvić-Urek, Miranda |
author_sort | Simčić, Daria |
collection | PubMed |
description | The etiology of BMS remains unknown. Role of various cytokines has been implicated in the development of BMS. The aim of this study was to evaluate levels of salivary IL-2 and IL-6 in patients with BMS, compared with age-matched healthy volunteers (control group). Whole saliva from 30 patients with BMS, age range 55–65, was tested for the presence of IL-6 and IL-2 by enzyme immunoassay. Control group consisted of 30 healthy participants, aged 55–65 years. Saliva IL-2 concentrations in BMS were significantly increased in patients compared to healthy subjects: mean 34.1 ± 9.7 versus 7.3 ± 3.0 pg/mL; P < .001. Patients with BMS had significantly higher concentrations of IL-6 compared to control: mean 30.8 ± 5.6 versus 5.2 ± 2.8 pg/mL; P < .001. In patients with BMS, IL-2 and IL-6 levels in saliva are elevated, correlating with the severity of illness. |
format | Text |
id | pubmed-1570384 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-15703842006-10-10 Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome Simčić, Daria Pezelj-Ribarić, Sonja Gržić, Renata Horvat, Jelena Brumini, Gordana Muhvić-Urek, Miranda Mediators Inflamm Short Communication The etiology of BMS remains unknown. Role of various cytokines has been implicated in the development of BMS. The aim of this study was to evaluate levels of salivary IL-2 and IL-6 in patients with BMS, compared with age-matched healthy volunteers (control group). Whole saliva from 30 patients with BMS, age range 55–65, was tested for the presence of IL-6 and IL-2 by enzyme immunoassay. Control group consisted of 30 healthy participants, aged 55–65 years. Saliva IL-2 concentrations in BMS were significantly increased in patients compared to healthy subjects: mean 34.1 ± 9.7 versus 7.3 ± 3.0 pg/mL; P < .001. Patients with BMS had significantly higher concentrations of IL-6 compared to control: mean 30.8 ± 5.6 versus 5.2 ± 2.8 pg/mL; P < .001. In patients with BMS, IL-2 and IL-6 levels in saliva are elevated, correlating with the severity of illness. Hindawi Publishing Corporation 2006 2006-02-06 /pmc/articles/PMC1570384/ /pubmed/16864905 http://dx.doi.org/10.1155/MI/2006/54632 Text en Copyright © 2006 Daria Simčić et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Communication Simčić, Daria Pezelj-Ribarić, Sonja Gržić, Renata Horvat, Jelena Brumini, Gordana Muhvić-Urek, Miranda Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome |
title | Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome |
title_full | Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome |
title_fullStr | Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome |
title_full_unstemmed | Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome |
title_short | Detection of Salivary Interleukin 2 and Interleukin 6 in Patients With Burning Mouth Syndrome |
title_sort | detection of salivary interleukin 2 and interleukin 6 in patients with burning mouth syndrome |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570384/ https://www.ncbi.nlm.nih.gov/pubmed/16864905 http://dx.doi.org/10.1155/MI/2006/54632 |
work_keys_str_mv | AT simcicdaria detectionofsalivaryinterleukin2andinterleukin6inpatientswithburningmouthsyndrome AT pezeljribaricsonja detectionofsalivaryinterleukin2andinterleukin6inpatientswithburningmouthsyndrome AT grzicrenata detectionofsalivaryinterleukin2andinterleukin6inpatientswithburningmouthsyndrome AT horvatjelena detectionofsalivaryinterleukin2andinterleukin6inpatientswithburningmouthsyndrome AT bruminigordana detectionofsalivaryinterleukin2andinterleukin6inpatientswithburningmouthsyndrome AT muhvicurekmiranda detectionofsalivaryinterleukin2andinterleukin6inpatientswithburningmouthsyndrome |