First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina

We describe the genetic diversity of currently transmitted strains of HIV-1 in men who have sex with men (MSM) in Buenos Aires, Argentina between 2000 and 2004. Nearly full-length sequence analysis of 10 samples showed that 6 were subtype B, 3 were BF recombinant and 1 was a triple recombinant of su...

Descripción completa

Detalles Bibliográficos
Autores principales: Pando, María A, Eyzaguirre, Lindsay M, Segura, Marcela, Bautista, Christian T, Marone, Rubén, Ceballos, Ana, Montano, Silvia M, Sánchez, José L, Weissenbacher, Mercedes, Ávila, María M, Carr, Jean K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570496/
https://www.ncbi.nlm.nih.gov/pubmed/16959032
http://dx.doi.org/10.1186/1742-4690-3-59
_version_ 1782130273438138368
author Pando, María A
Eyzaguirre, Lindsay M
Segura, Marcela
Bautista, Christian T
Marone, Rubén
Ceballos, Ana
Montano, Silvia M
Sánchez, José L
Weissenbacher, Mercedes
Ávila, María M
Carr, Jean K
author_facet Pando, María A
Eyzaguirre, Lindsay M
Segura, Marcela
Bautista, Christian T
Marone, Rubén
Ceballos, Ana
Montano, Silvia M
Sánchez, José L
Weissenbacher, Mercedes
Ávila, María M
Carr, Jean K
author_sort Pando, María A
collection PubMed
description We describe the genetic diversity of currently transmitted strains of HIV-1 in men who have sex with men (MSM) in Buenos Aires, Argentina between 2000 and 2004. Nearly full-length sequence analysis of 10 samples showed that 6 were subtype B, 3 were BF recombinant and 1 was a triple recombinant of subtypes B, C and F. The 3 BF recombinants were 3 different unique recombinant forms. Full genome analysis of one strain that was subtype F when sequenced in pol was found to be a triple recombinant. Gag and pol were predominantly subtype F, while gp120 was subtype B; there were regions of subtype C interspersed throughout. The young man infected with this strain reported multiple sexual partners and sero-converted between May and November of 2004. This study reported for the first time the full genome analysis of a triple recombinant between subtypes B, C and F, that combines in one virus the three most common subtypes in South America.
format Text
id pubmed-1570496
institution National Center for Biotechnology Information
language English
publishDate 2006
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-15704962006-09-21 First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina Pando, María A Eyzaguirre, Lindsay M Segura, Marcela Bautista, Christian T Marone, Rubén Ceballos, Ana Montano, Silvia M Sánchez, José L Weissenbacher, Mercedes Ávila, María M Carr, Jean K Retrovirology Short Report We describe the genetic diversity of currently transmitted strains of HIV-1 in men who have sex with men (MSM) in Buenos Aires, Argentina between 2000 and 2004. Nearly full-length sequence analysis of 10 samples showed that 6 were subtype B, 3 were BF recombinant and 1 was a triple recombinant of subtypes B, C and F. The 3 BF recombinants were 3 different unique recombinant forms. Full genome analysis of one strain that was subtype F when sequenced in pol was found to be a triple recombinant. Gag and pol were predominantly subtype F, while gp120 was subtype B; there were regions of subtype C interspersed throughout. The young man infected with this strain reported multiple sexual partners and sero-converted between May and November of 2004. This study reported for the first time the full genome analysis of a triple recombinant between subtypes B, C and F, that combines in one virus the three most common subtypes in South America. BioMed Central 2006-09-07 /pmc/articles/PMC1570496/ /pubmed/16959032 http://dx.doi.org/10.1186/1742-4690-3-59 Text en Copyright © 2006 Pando et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Report
Pando, María A
Eyzaguirre, Lindsay M
Segura, Marcela
Bautista, Christian T
Marone, Rubén
Ceballos, Ana
Montano, Silvia M
Sánchez, José L
Weissenbacher, Mercedes
Ávila, María M
Carr, Jean K
First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina
title First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina
title_full First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina
title_fullStr First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina
title_full_unstemmed First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina
title_short First report of an HIV-1 triple recombinant of subtypes B, C and F in Buenos Aires, Argentina
title_sort first report of an hiv-1 triple recombinant of subtypes b, c and f in buenos aires, argentina
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570496/
https://www.ncbi.nlm.nih.gov/pubmed/16959032
http://dx.doi.org/10.1186/1742-4690-3-59
work_keys_str_mv AT pandomariaa firstreportofanhiv1triplerecombinantofsubtypesbcandfinbuenosairesargentina
AT eyzaguirrelindsaym firstreportofanhiv1triplerecombinantofsubtypesbcandfinbuenosairesargentina
AT seguramarcela firstreportofanhiv1triplerecombinantofsubtypesbcandfinbuenosairesargentina
AT bautistachristiant firstreportofanhiv1triplerecombinantofsubtypesbcandfinbuenosairesargentina
AT maroneruben firstreportofanhiv1triplerecombinantofsubtypesbcandfinbuenosairesargentina
AT ceballosana firstreportofanhiv1triplerecombinantofsubtypesbcandfinbuenosairesargentina
AT montanosilviam firstreportofanhiv1triplerecombinantofsubtypesbcandfinbuenosairesargentina
AT sanchezjosel firstreportofanhiv1triplerecombinantofsubtypesbcandfinbuenosairesargentina
AT weissenbachermercedes firstreportofanhiv1triplerecombinantofsubtypesbcandfinbuenosairesargentina
AT avilamariam firstreportofanhiv1triplerecombinantofsubtypesbcandfinbuenosairesargentina
AT carrjeank firstreportofanhiv1triplerecombinantofsubtypesbcandfinbuenosairesargentina

Ejemplares similares